Quick Answer
Several STDs increase miscarriage risk: syphilis causes stillbirth in up to 40% of untreated cases, bacterial vaginosis doubles the risk of second-trimester loss, and untreated chlamydia/gonorrhea may contribute through inflammation. Early prenatal screening and treatment reduce these risks to near-zero.
- Syphilis: the most dangerous to pregnancy — up to 40% of untreated infections result in stillbirth.
- BV: associated with 2x risk of second-trimester miscarriage and preterm delivery.
- Chlamydia/gonorrhea: weaker evidence, but PID during pregnancy raises risks.
- Treatment works: penicillin for syphilis, metronidazole for BV, ceftriaxone/azithromycin for chlamydia/gonorrhea.
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The mechanism is inflammation and placental damage. Untreated infections create a hostile uterine environment that can trigger contractions, premature rupture of membranes, or direct fetal infection.
After miscarriage
If you experienced a miscarriage and were not screened for STIs, consider testing now. Knowing whether an infection contributed helps guide future pregnancy planning and treatment.
Sources & Further Reading
- CDC — Sexually Transmitted Infections
- CDC STI Treatment Guidelines
- WHO — Sexually transmitted infections fact sheet
- MedlinePlus — Sexually Transmitted Diseases
Figures reflect CDC surveillance and WHO estimates; they are population statistics, not personal risk predictions.