Quick Answer

Mpox caused a global outbreak in 2022, spreading through close skin contact during sexual activity. It causes painful pustular lesions and is preventable with the JYNNEOS vaccine. The outbreak was contained through vaccination and behavior change.

  • Viral (orthopoxvirus)
  • 2022 global outbreak: primarily sexual transmission
  • Symptoms: painful pustular lesions, fever, lymphadenopathy
  • Vaccine: JYNNEOS (2 doses), highly effective

Context Most Pages Skip

Mpox (formerly monkeypox) was the unexpected STI outbreak of 2022, demonstrating that new sexually transmitted infections can emerge anytime.

Key Facts

The 2022 outbreak was driven by close skin-to-skin contact during sexual activity. The JYNNEOS vaccine is effective for both pre-exposure and post-exposure prophylaxis. Most cases were self-limiting, but lesions can be extremely painful.

⚕️ This page is educational and does not replace advice from a licensed clinician. If you may have been exposed to an STI, get tested — most infections are manageable, and many are fully curable.

Sources & Further Reading

Figures reflect CDC surveillance and WHO estimates; they are population statistics, not personal risk predictions.